Facing the huge threat of relegation in the domestic league, the home side currently sits at the bottom of the standings with underwhelming form this term.
With limited overall squad strength, La Calera Union is highly likely to make massive line-up rotations for this Chile Cup fixture, as securing their top-flight status remains their absolute top priority over cup progress.
Their opponents Coquimbo have posted far more satisfying league performances so far, sitting 8th on the league table at present. That said, their away form this season has been far from convincing.
Both sides are expected to bring full fighting spirit to this tie, making the final outcome far from a straightforward call.